A WHOLE LABORATORY IN A SINGLE DROPLET

The instrument is a compact system that seamlessly complements other laboratory instruments, including automated screening platforms. Its miniaturization to the millimeter scale delivers a 1,000-fold leap in productivity.

BENEFITS OF MILLIFLUIDIC TECHNOLOGY:

Miniaturization

A droplet of a hundred nanoliters to a few picoliters replaces a Petri dish or an incubator to grow bacteria, fungi, algae or yeast.

Automation

Preparation, incubation, analysis and high-throughput sorting operations are done by a single instrument.

INDIVIDUAL PROCESSING

Each droplet is a reservoir handled individually: choose the initial composition, add compounds, sort droplets of interest.

PARALLELIZATION

Because of the high number of droplets, we can observe many reactions in parallel, without cross-contamination between cultures or evaporation.

Microorganisms are cultivated, analyzed and recovered automatically in the MilliDrop Analyzer.

HOW DOES IT WORK?

1 - GENERATION


  • Up to 10 technical replicates per condition
  • Little time spent in front the machine
  • Up to 94 different conditions
  • Small sample volume

2 - incubation


  • No evaporation
  • Homogeneous growth conditions
  • Temperature range from 15 to 50°C

3 - Mesurement


  • Early detection
  • 1000 isolated reactors measured independently
  • Kinetic measurements using up to 4 fluorescence channels

4 - Sorting


  • Identify the most interesting droplets
  • Collect the droplets of interest in a 96-well plate
  • Sorted reactors ready for DNA/RNA extraction